Which cells in human body have no nucleus?

In the human body, mature red blood cells (erythrocytes) are unique because they lack a nucleus. During the process of erythropoiesis, immature red blood cells possess a nucleus, but it is ejected as they mature to provide more space for hemoglobin [2]. This adaptation increases the cell's capacity to carry oxygen and results in their characteristic biconcave shape. In contrast, other cells mentioned have nuclei: muscle cells are often multinucleated, containing hundreds of nuclei to support their high protein demands and length [3]. Phagocytic cells, such as macrophages, are eukaryotic cells that contain a nucleus to manage their complex immune functions [2]. Ciliated cells, which are specialized epithelial cells, also maintain a nucleus to regulate cellular activities. Therefore, red blood cells are the only anucleate cells among the given options.

Sources

1. [2] https://www.ncbi.nlm.nih.gov/books/NBK2263/
2. [3] Science , class X (NCERT 2025 ed.) > Chapter 7: How do Organisms Reproduce? > How do Organisms Reproduce? CHAPTER7 > p. 116