To prevent heart problems, blood of a normal healthy person should have 1. low cholesterol level. 2. high HDL level. 3. high VLDL level: 4. high LDL level. Select the correct answer using the code given below:

To maintain cardiovascular health and prevent heart problems, a normal healthy person should maintain low total cholesterol and high levels of High-Density Lipoprotein (HDL). HDL is commonly referred to as 'good' cholesterol because it facilitates 'reverse cholesterol transport,' removing excess cholesterol from the arteries and returning it to the liver for excretion [4]. Conversely, Low-Density Lipoprotein (LDL) and Very Low-Density Lipoprotein (VLDL) are considered 'bad' or atherogenic lipoproteins. High levels of LDL lead to plaque buildup in blood vessels, increasing the risk of heart attack and stroke. VLDL primarily carries triglycerides, and elevated levels of both VLDL and LDL are major risk factors for coronary artery disease [2]. Therefore, a healthy profile requires low total cholesterol (including low LDL and VLDL) and high HDL levels to protect against atherosclerosis.

Sources

1. [2] https://pmc.ncbi.nlm.nih.gov/articles/PMC3504986/
2. [4] https://medlineplus.gov/cholesterollevelswhatyouneedtoknow.html