Stem Cell Therapy (SCT) is not useful for the treatment of which one of the following ailments?

Stem cell therapy (SCT) is a revolutionary field in regenerative medicine with diverse applications. It is extensively used in treating various forms of cancer, particularly blood cancers like leukemia and lymphoma, where hematopoietic stem cell transplants restore blood-forming cells after intensive chemotherapy [t1, t7]. Research also supports its use in treating brain injuries by mobilizing neural stem cells to repair damaged brain tissue [t2, t9]. Furthermore, SCT shows significant promise in treating vision impairment, specifically through retinal regeneration and corneal repair [t3, c3]. However, while research into mesenchymal stem cells for kidney regeneration is ongoing [t5], established clinical guidelines often list significant comorbidities, such as renal failure, as a relative contraindication for certain stem cell procedures like allogeneic hematopoietic stem cell transplantation [t8]. Therefore, among the options provided, kidney failure is currently the least established indication for standard stem cell therapy.

Sources

1. [1] https://www.cancer.gov/about-cancer/treatment/types/stem-cell-transplant
2. [2] https://www.sciencedirect.com/science/article/pii/S0085253815510661
3. [3] https://pmc.ncbi.nlm.nih.gov/articles/PMC12096755/
4. [4] Science , class X (NCERT 2025 ed.) > Chapter 10: The Human Eye and the Colourful World > QUESTIONS > p. 165