Which one of the following blood cells type secrete large number of antibodies during an immune response of the body ?

Lymphocytes, specifically B lymphocytes (B cells), are the primary blood cells responsible for the production and secretion of antibodies during an immune response. When a B lymphocyte is activated by an antigen, it differentiates into a specialized effector cell known as a plasma cell [1]. These plasma cells function as 'antibody factories,' capable of synthesizing and secreting thousands of antibody molecules per second to neutralize pathogens [1]. While other white blood cells like neutrophils and monocytes are involved in phagocytosis and the innate immune response, they do not secrete antibodies [2]. Eosinophils are primarily involved in combating parasitic infections and allergic reactions. Therefore, among the given options, lymphocytes are the specific cell type that gives rise to the large-scale antibody production necessary for humoral immunity [1].

Sources

1. [1] https://www.ncbi.nlm.nih.gov/books/NBK556082/
2. [2] https://www.ncbi.nlm.nih.gov/books/NBK539801/